Your endocannabinoid system (ECS) was discovered in the 1980's. All vertebrates, and even some invertebrates, have this amazing system of receptors and transmitters within the body. These receptors are found in all tissues, but predominantly in the brain and gut.

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There are three known/named receptors (CB1, CB2 and Anandamide receptor) and others that have been found, but not yet named. The ECS plays a role in pain and inflammation reduction, decrease of anxiety and stress, and sleep and wake cycles.

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**In the GI system, CB2 and Anandamide recpetors protect the tract from inflammation and abnormally high gastric and enteric secretions.

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**In the Immune system, all three receptors work to regulate immunity by suppressing pro-inflammatory cytokine production.

 

**In the Central Nervous System, CB1 and CB2 facilitate the generation of new neurons and are involved in neuro-protection, regulation of motor activity, synaptic plasticity, and control of certain memory processing.

 

**Metabolism. CB1 and CB2 maintain balance by controlling food intake and metabolic functions such as energy storage, nutrient transport, and even modulating insulin sensitivity.

 

**Hormones. CB2 and Anandamide receptors play a significant role in hypothalamic function which regulates metabolism, reproduction, and the body's response to stress.

 

**Muscles. The CB2 receptor enhances stamina by regulating blood sugar and encourages the "runner's high".

 

**Bones. The CB2 receptor plays an important role in regulating bone mass and regrowth.